New Smartphone Based Colorimetric Method Development and Validation of Drugs Containing Nitrogen, Phosphorus and Sulphur
نویسندگان
چکیده
Colorimetry is a method for determining the concentration of coloured substances in solution. The intensity colour directly proportional to compound being measured. Smartphone based colorimetry has grown popularity as analytical instruments due their low cost and ability collect, store process data all one device. In smartphone colorimetry, camera on phone serves detector. colorimetric UV both are detection intensity. ammonium metavanadate having different oxidation states it produce colours its state. +5-oxidation state shows yellow colour, +4 blue +3 green +2 purple colour. reagent orange red colour; however, transforms into complex when reacts with drugs containing nitrogen, phosphorus sulphur structure. this article developed exhibits good linearity Correlation coefficient about 0.998(Amoxicillin trihydrate), 0.998 (Silodosin) 0.999(Sofosbuvir). With increasing concentrations API, increases. All photographs were taken analysed using photometrix PRO software. This application converts an image RGB histogram regression models included application. By Photometrix technique, percent RSD three was Using statistical tool i.e two paired test procedures drugs, results show that equally significant.
 Keywords: spectrophotometry, PRO, Histogram
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ژورنال
عنوان ژورنال: Journal of Drug Delivery and Therapeutics
سال: 2022
ISSN: ['2250-1177']
DOI: https://doi.org/10.22270/jddt.v12i3-s.5503